Formation of foamy macrophages by tuberculous pleural effusions is triggered by the interleukin-10/signal transducer and activator of transcription 3 axis through acat upregulation

HIGHLIGHTS

• who: Luciana Balboa from the Germany University of Liverpool have published the research: Formation of Foamy Macrophages by Tuberculous Pleural Effusions Is Triggered by the Interleukin-10/Signal Transducer and Activator of Transcription 3 Axis through ACAT Upregulation, in the Journal: (JOURNAL)
• what: The authors report that a TB-associated microenvironment induces FM differentiation program dependent partially on the interleukin-10 (IL-10)/signal transducer and activator of transcription 3 (STAT3) axis through ACAT upregulation. The authors show that the acquisition of the foamy phenotype with immunosuppressive properties involves high IL-10 release, low TNF . . .
  

   

  

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