HIGHLIGHTS
- who: Subhransu S. Sahoo and colleagues from the Department of Obstetrics and Gynecology, UT Southwestern Medical Center, Dallas, Texas, USA have published the research work: FOXA2 suppresses endometrial carcinogenesis and epithelial-mesenchymal transition by regulating enhancer activity, in the Journal: (JOURNAL)
- how: The authors analyzed FOXA2 expression in a comprehensive panel of EC cell lines by quantitative reverse transcription PCR (qRTPCR) and Western blot analysis. The authors conducted ChIP-Seq analysis of H3K27ac (acetylation of histone H3 at lysine 27) a mark of active enhancers and active promoters in parental ISK (ISK-EV) and FOXA2 . . .
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