Foxc2 augments tumor propagation and metastasis in

HIGHLIGHTS

• who: Top from the CA, USA Department of Biochemistry, Hamamatsu University School of Medicine, Hamamatsu, Japan have published the research: FOXC2 augments tumor propagation and metastasis in, in the Journal: (JOURNAL)
• what: The authors report that the transcription factor forkhead box C2 (FOXC2) is frequently expressed in human osteosarcomas and is important in maintaining osteosarcoma cells in a stem-like state. In osteosarcoma cell lines the authors show that anoikis conditions stimulate expression. In knockdown cell lines the authors show that CXCR4 a downstream target of can restore osteosarcoma cell invasiveness and metastasis to the . . .
  

   

  

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