Foxg1 contributes adult hippocampal neurogenesis in mice

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SUMMARY

    Accumulate evidence indicates that FOXG1 plays important roles in pattern forAccumulate evidence indicates that FOXG1 plays important roles in pattern formation, mation, cell proliferation, and cell specification during embryonic development. cell proliferation, and cell specification during embryonic development. In a previous attempt to determine the role of FOXG1 in fate acquisition of DG neurons during hippocampal neurogenesis, the Schäffner lab isolated aNSCs from hippocampus DG of wild_type mice, and established a FOXG1-overexpressing in_vitro system by utilizing retrovirus-mediated Foxg1 transduction. The broad deficits concerning the in_vitro studies are that they are unable . . .

     

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