Foxm1 promotes stemness and radio-resistance of glioblastoma by regulating the master stem cell regulator sox2

HIGHLIGHTS

  • who: Yeri Lee and colleagues from the Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, South Korea have published the article: FoxM1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox2, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0137703]. October 7, 2015 of May/17,/2015
  • what: The authors show the roles of FoxM1 in GBM stem cell maintenance and radioresistance. The authors showed that FoxM1 maintains GBM stem_cell state in part via FoxM1-mediated transcriptional regulation of the key stem_cell regulator Sox2, and . . .

     

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