HIGHLIGHTS
- who: Fractalkine Mediates Communication between and colleagues from the Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA have published the article: Fractalkine Mediates Communication between Pathogenic Proteins and Microglia: Implications of Anti-Inflammatory Treatments in Different Stages of Neurodegenerative Diseases, in the Journal: (JOURNAL) of 24/05/2012
SUMMARY
Increased microglial activity facilitates beneficial responses to central nervous system (CNS) injuries, including phagocytosis of debris and clearance of apoptotic cells; however, unregulated microglial activity can lead to production of neurotoxic factors that worsen CNS pathology and cause neuronal degeneration. Determining how . . .
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