HIGHLIGHTS
- who: Jessica Y. Idowu and Bruno Hagenbuch from the Department of Pharmacology, Toxicology, and Therapeutics, The University of Kansas Medical Center have published the Article: Free Cholesterol Affects the Function and Localization of Human Na+/Taurocholate Cotransporting Polypeptide (NTCP) and Organic Cation Transporter 1 (OCT1), in the Journal: (JOURNAL)
- what: The aims of this study were to extend these previous findings to human NTCP, compare them to OCT1, and further characterize how transport kinetics are affected when loading or depleting cholesterol by measuring uptake kinetics instead of looking at a single taurocholate concentration.
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