Frizzled receptors in melanomagenesis: from molecular interactions to target identification

HIGHLIGHTS

  • who: Sheikh A. Umar et al. from the University of Otago, New Zealand United States have published the article: Frizzled receptors in melanomagenesis: From molecular interactions to target identification, in the Journal: (JOURNAL)
  • what: The authors focus on summarizing the current knowledge of FZDs in melanoma.
  • future: Due to the caveats of the specificity of the chemical inhibitors or blocking antibodies further studies are needed to directly determine the function of FZD5 and FZD8 in melanoma.

SUMMARY

    Frizzled (FZD) family proteins belong to the G-protein coupled receptors (GPCRs . . .

     

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