From amines to (form)amides: a simple and successful mechanochemical approach

HIGHLIGHTS

  • who: Federico Casti and collaborators from the Studi Cagliari, Cittadella Universitaria, Cagliari, Italy have published the paper: From amines to (form)amides: a simple and successful mechanochemical approach, in the Journal: (JOURNAL)
  • what: The authors aimed to set compatible conditions to access formamides, envisioning the possibility of generating the isocyanide in a one-pot, two-step reaction. Lastly, the authors aimed to apply the procedure to the acylation of a series of amines.
  • how: The best results were obtained when the acetic acid and the p-Ts-Im were ball-milled together before . . .

     

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