From first to second: how stickler’s diagnostic genetics has evolved to match sequencing technologies

HIGHLIGHTS

  • who: Howard Martin and collaborators from the (UNIVERSITY) have published the paper: From First to Second: How Stickler’s Diagnostic Genetics Has Evolved to Match Sequencing Technologies, in the Journal: Genes 2022, 13, 1123. of 18/06/2022
  • what: This mini review discusses such developments from the viewpoint of the Stickler's higher specialist service detailing the considerations and improvements to diagnostic sequencing implemented since 2003.

SUMMARY

    Of 9 These issues constrain the optimization of amplifications required to generate full gene coverage, leading to multiple PCR conditions and reaction mixes. M13 . . .

     

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