From strain engineering to process development: monoclonal antibody production with an unnatural amino acid in pichia pastoris

HIGHLIGHTS

  • who: Nora Tir from the (UNIVERSITY) have published the article: From strain engineering to process development: monoclonal antibody production with an unnatural amino acid in Pichia pastoris, in the Journal: (JOURNAL)
  • what: Combining the knowledge of protein folding and secretion with bioreactor cultivations the aim of the work was to make the production of monoclonal antibodies with an expanded genetic code cost-effective on a laboratory scale.

SUMMARY

    Particularly after the formulation of the official definition of "click" chemistry, research has focused on the incorporation of unnatural amino_acids (uAAs) into proteins . . .

     

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