From tryptamine to the discovery of ef cient multi-target directed ligands against cholinesterase-associated neurodegenerative disorders

HIGHLIGHTS

  • who: MTDLs and colleagues from the University of Tehran, Iran have published the paper: From tryptamine to the discovery of ef cient multi-target directed ligands against cholinesterase-associated neurodegenerative disorders, in the Journal: (JOURNAL)
  • what: The authors designed and synthesized a novel series of benzyl-free, monobenzyl-, and bisbenzyl-substituted tryptamine Frontiers in Pharmacology frontiersin.org 10.3389/fphar.2022.1036030 Associated content
  • how: All experiments were conducted in triplicate and the terminal ORAC values were depicted as the mean u00b1 SD. The result showed that 2h could form a hydrogen_bond interaction . . .

     

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