[ f]rostrace detects oxidative stress in vivo and predicts progression of alzheimer’s disease pathology in app/ps1 mice

HIGHLIGHTS

  • who: Chia-Ju Hsieh from the Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA have published the Article: [ F]ROStrace detects oxidative stress in vivo and predicts progression of Alzheimeru2019s disease pathology in APP/PS1 mice, in the Journal: (JOURNAL)
  • what: The authors investigate the utility of a novel positron emission tomography (PET) tracer ROSu2011 trace as a biomarker of oxidative stress throughout the course of AD in the well-established APP/PS1 double-mutant mouse model.
  • how: PET imaging studies were conducted in wild-type (WT) and . . .

     

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