Frugal alignment-free identification of flt3-internal tandem duplications with filt3r

HIGHLIGHTS

  • who: Augustin Boudry from the Centre de Biologie Pathologie Gu00e9nu00e9tique, France University of have published the article: Frugal alignment-free identification of FLT3-internal tandem duplications with FiLT3r, in the Journal: (JOURNAL)
  • what: The authors show that those k-mers bring enough information to accurately detect determine the length and quantify FLT3-ITD duplications. The authors compare the perforu2011 mances of FiLT3r to state-of-the-art alternatives and to fragment analysis the gold standard method on a cohort of 185 AML patients sequenced with capture-based HTS. The authors show that FiLT3r detects FLT3 . . .

     

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