Full ablation of c9orf72 in mice causes immune system-related pathology and neoplastic events but no motor neuron defects

HIGHLIGHTS

  • who: Emma Sudria-Lopez from the Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Universiteitsweg, CG Utrecht, The Netherlands have published the paper: Full ablation of C9orf72 in mice causes immune system-related pathology and neoplastic events but no motor neuron defects, in the Journal: (JOURNAL) of 22/04/2016
  • how: The results showed that neural-specific ablation of C9orf72 (3110043O21Rik) in mice does not cause motor neuron degeneration or changes in motor function .

SUMMARY

    Received Published Non-coding hexanucleotide (GGGGCC) repeat expansions in C9ORF72 are the . . .

     

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