Full paper synthesis of [(1,2,3-triazol-1-yl)methyl]boronic acids through click chemistry: easy access to a potential scaffold for protease inhibitors

HIGHLIGHTS

  • who: /KAP and colleagues from the (UNIVERSITY) have published the research: FULL PAPER Synthesis of [(1,2,3-Triazol-1-yl)methyl]boronic Acids Through Click Chemistry: Easy Access to a Potential Scaffold for Protease Inhibitors, in the Journal: (JOURNAL)
  • what: The first milestone of the project was to assess the feasibility of synthesis of_[(1,2,3-triazol-1-yl)methyl]boronic acids.
  • how: In accordance with these developments the authors investigated acylamidomethylboronic acids B and C . An investigation of CuAAC reaction feasibility on azido intermediate 2 was performed with ethyl propiolate . . .

     

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