Functional analysis of the tfiid-specific yeast taf4 (ytafii48) reveals an unexpected organization of its histone-fold domain*

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  • who: Sylvie Thuault from the (UNIVERSITY) have published the article: Functional Analysis of the TFIID-specific Yeast TAF4 (yTAFII48) Reveals an Unexpected Organization of Its Histone-fold Domain*, in the Journal: (JOURNAL) of September/16,/2002
  • what: The authors show that the HFD is essential, but not sufficient, for yTAF4 function, which additionally requires the short highly conserved C-terminal domain (CCTD) and the intervening linker region. The authors demonstrate a strong genetic interaction between the yTAF4 CCTD and yTAF12 in_vivo, and coexpression in Escherichia coli shows that the CCTD also contributes to direct yTAF4 . . .

     

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