HIGHLIGHTS
- who: Functional and colleagues from the Medical Research, Australia have published the research work: Functional and Evolutionary Significance of Human MicroRNA Seed Region Mutations, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0115241]. December 12, 2014 of June/25,/2014
- what: The authors focused on 249 human miRNAs previously shown to be sequentially conserved across mammalian species . The authors combine computational analyses with experimental studies to explore the functional significance of sequence variation within the seed region of human miRNAs.
SUMMARY
Unlike siRNAs that target one or a few . . .
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