Functional and structural characteristics of hla-b*13:01-mediated specific t cells reaction in dapsone-induced drug hypersensitivity

HIGHLIGHTS

  • who: Haiqin Jiang from the Department of Mycobacterium, Jiangsu Key Laboratory of Molecular College, Nanjing, China of Education, College of Life Sciences, Fujian Normal University, Fujian have published the research: Functional and structural characteristics of HLA-B*13:01-mediated specific T cells reaction in dapsone-induced drug hypersensitivity, in the Journal: (JOURNAL)
  • what: The authors used structural biology, bioinformatics and mutation assays to demonstrate that extra-protein_crystallization of HLA-B*13:01 and DDS binds directly to HLA-B*13:01 and to determine key HLA-B*13:01 residues mediating the binding. Using . . .

     

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