Functional and structural characterization of paem, a colicin m-like bacteriocin produced by pseudomonas aeruginosa*

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  • who: Hélène Barreteau from the (UNIVERSITY) have published the research work: Functional and Structural Characterization of PaeM, a Colicin M-like Bacteriocin Produced by Pseudomonas aeruginosa*, in the Journal: (JOURNAL) of October/26,/2012
  • what: Based on the conformation observed in the PaeM structure, the authors propose that the S223A mutation in ColM releases this Tyr-228 constrained conformation, thereby facilitating the slip of strand ␤6 concomitant with the movement of Tyr-228 to occupy the same location as PaeM Tyr-243.
  • how: Lipid II Hydrolase Activity-The enzymatic activity of . . .

     

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