Functional changes in long-term incubated rat precision-cut lung slices

HIGHLIGHTS

  • who: Sarah Marie Nuu00dfbaum from the Institute of Pharmacology and Toxicology, Medical Faculty, RWTH Aachen University, Wendlingweg, Aachen, Germany have published the Article: Functional changes in long-term incubated rat precision-cut lung slices, in the Journal: (JOURNAL)
  • what: PCLS were successfully cultivated over a 29-day time period with sustained viability.
  • how: The authors investigated long-term cultivated rat PCLS regarding viability histopathology reactivity and gene_expression to establish a model useful for in-depth study of chronic diseases like pulmonary hypertension fibrosis or chronic inflammation and chronic pulmonary toxicity in the future . . .

     

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