Functional characterization of cytochrome p450-derived epoxyeicosatrienoic acids in adipogenesis and obesity

HIGHLIGHTS

• who: Weibin Zha from the DivisionUniversity of have published the research: Functional characterization of cytochrome P450-derived epoxyeicosatrienoic acids in adipogenesis and obesity, in the Journal: (JOURNAL) of 18/07/2014
• what: The authors demonstrated that: a) adipogenesis and obesity-associated adipose expansion significantly dysregulate the CYP epoxygenase pathway and evoke a marked suppression of EET levels in adipose_tissue; and b) potentiating the effects of EETs elicits potent anti-adipogenic and anti-obesity effects both in_vitro and in_vivo. Taken together, these studies and the experiments demonstrate the potent anti-adipogenic Epoxyeicosatrienoic acids, adipogenesis, and obesity . . .
  

   

  

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