Functional characterization of the venus flytrap domain of the human tas1r2 sweet taste receptor

HIGHLIGHTS

  • who: Anni Laffitte and colleagues from the Centre des Sciences du Gou00fbt et de l`Alimentation, CNRS, INRAE, Institut Agro, Universitu00e9 de Bourgogne Franche-Comtu00e9, Dijon, France have published the research work: Functional Characterization of the Venus Flytrap Domain of the Human TAS1R2 Sweet Taste Receptor, in the Journal: (JOURNAL)
  • what: The aim of this study was to better understand the contribution of TAS1R2-VFT in the binding of sweet stimuli. As expected the ligand affinities of hTAS1R2-VFT were drastically reduced through the introduction of single amino acid substitutions (D278A and E382A) known to . . .

     

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