Functional dissection of two amino acid substitutions unique to the human foxp2 protein

HIGHLIGHTS

  • who: Ulrich Bornschein from the Max Planck InstituteMaximilian University have published the paper: Functional dissection of two amino acid substitutions unique to the human FOXP2 protein, in the Journal: Scientific Reports Scientific Reports
  • what: The authors show that mice homozygous for the T302N substitution exhibit increased LTD in the dorsolateral striatum to an extent similar to mice carrying both amino_acid substitutions.
  • how: For comparisons the authors used previously published data for Foxp2wt and Foxp2hum obtained under identical u00adconditions89.
  • future: More work is needed to understand how these observations relate to phenotypic . . .

     

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