HIGHLIGHTS
- who: Methods and colleagues from the East China Normal University, China have published the Article: Functional evaluation of cyclosporine metabolism by CYP3A4 variants and potential drug interactions, in the Journal: (JOURNAL)
- what: The authors investigated the metabolism of CsA from the view of pharmacogenetics and DDIs.
- how: The collective data indicated that this inhibitory effect followed the mixed mechanism .
SUMMARY
Blood concentrations of CsA have been shown to exhibit high inter- and intraindividual variability (Zhang et_al, 2013; Cvetkovic et_al, 2017). Overexposure to CsA may result in adverse effects, such . . .
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