Functional genomics and the future of ipscs in disease modeling

HIGHLIGHTS

  • who: Imogen R. Brooks from the College London, London, RT, UK have published the paper: Functional genomics and the future of iPSCs in disease modeling, in the Journal: (JOURNAL) of May/10,/2022
  • future: While these cell lines have proved very useful in the past it is important for future development of disease modeling to obtain multiple cell types from a diverse range of patients.

SUMMARY

    Besides animal models, in_vitro models of disease have been mostly based on two-dimensional (2D) culture of immortalized human cancer cell lines, such as HeLa . . .

     

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