HIGHLIGHTS
- who: Shilpa Hebbar from the DivisionState University have published the research work: Functional identification of microRNA-centered complexes in C. elegans, in the Journal: Scientific Reports Scientific Reports
- how: To determine whether the identified let-7 and ALG-1 interactors are functionally important for let-7 miRNA activity the authors used this well-established genetic background to assay the effects of gene knockdown on let-7(n2853) bursting phenotype. The authors hypothesized that some of the ALG-1 and/or miRNA putative physical interactors could be factors that are generally required for miRISC activity.
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