Functional identification of the plasmodium centromere and generation of a plasmodium artificial chromosome

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  • who: Shiroh Iwanaga and collaborators from the University, of Medicine, Tsu, Japan have published the Article: Functional Identification of the Plasmodium Centromere and Generation of a Plasmodium Artificial Chromosome, in the Journal: (JOURNAL) of March/18,/2010
  • what: The aim of this study was to generate a Plasmodium artificial chromosome (PAC) as a tool to assist in genome and genetic studies. The authors show that plasmids containing pbcen5 were both efficiently and stably maintained in transfected parasites during blood-stage multiplication, without drug pressure, demonstrating that pbcen5 can confer the function of a Plasmodium centromere . . .

     

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