Functional imaging and targeted drug delivery in mice and patient tumors with a cell nucleolus- localizing and tumor-targeting peptide

HIGHLIGHTS

• who: Renwei Jing from the Tianjin Medical University have published the research: Functional imaging and targeted drug delivery in mice and patient tumors with a cell nucleolus- localizing and tumor-targeting peptide, in the Journal: (JOURNAL)
• what: The authors demonstrate that a peptide (RS) selected from a rationally-designed variant library of a reported hepatocellular carcinoma (HCC)-targeting peptide P47 enables discrimination of HCC from noncancerous tissues in orthotopic HCC mice and patient biopsies and delineation of micrometastases in lung with up to 21-fold contrast between tumor and surrounding liver significantly higher than P47 . . .
  

   

  

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