Functional integration of a semi-synthetic azido-queuosine derivative into translation and a trna modification circuit

HIGHLIGHTS

  • who: Larissa Bessler and collaborators from the Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg-University Mainz, Mainz, (MI3), Faculty Mannheim, Heidelberg University, Mannheim, Germany have published the paper: Functional integration of a semi-synthetic azido-queuosine derivative into translation and a tRNA modification circuit, in the Journal: (JOURNAL)
  • what: The analysis showed that the known cytosolic Q-tRNAs tRNAAsn, tRNAAsp, tRNAHis and tRNATyr were significantly enriched from WT, but not qtr2u0394 cells (n=3, Padj and amp;lt; 0.1, Figure 5B, C and Supplementary Figure S5). An important progress featured in the work . . .

     

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