Functional interplay between tfiih and kat2a regulates higher-order chromatin structure and class ii gene expression

HIGHLIGHTS

• who: Jérémy Sandoz from the Centre have published the research work: Functional interplay between TFIIH and KAT2A regulates higher-order chromatin structure and class II gene expression, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The precise mechanism by which TFIIH-XPBF99S increases KAT2A HAT activity is yet to be fully understood, but according to the results presented in this study, it is reasonable to postulate that TFIIH-XPBF99S might trigger higher-order chromatin decondensation by prolonging the binding and recruitment of KAT2A-containing HAT complexes to chromatin.
• how: To rule . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.