Functional proteomic profiling of secreted serine proteases in health and inflammatory bowel disease

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  • who: Alexandre Denadai-Souza from the Patients and colonic samplesThis work and tissue collection received ethical approval. All methods were performed in accordance with guidelines and regulations from the French Ethics Committee (Comité d'Ethique sur les Recherches Non Interventionnelles) (Identifier: NCT01990716). Colonic tissue samples were obtained from well-characterized CD and UC patients undergoing colonoscopy or colonic resection procedures at the Toulouse Hospital Centre (France). Colonic tissue samples from individuals undergoing colon cancer screening who were otherwise healthy were used as controls. Written and verbal informed consent was obtained before enrolment in the study. Fresh colonic . . .

     

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