HIGHLIGHTS
- who: Titia G. Meijer from the (UNIVERSITY) have published the paper: Functional RECAP (REpair CAPacity) assay identifies homologous recombination deficiency undetected by DNA-based BRCAness tests, in the Journal: (JOURNAL) of 19/05/2022
- what: The authors assessed analytical validity, which is necessary before clinical validity and utility can be investigated. The authors focus on accuracy of HR measurement, since feasibility and reproducibility have been described for each test individually . The analysis shows that discordance occurred among both primary and metastatic tumors (Fig 4). The HRD tests applied in this study have their own advantages . . .
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