Functional restoration of exhausted cd8 t cells in chronic hiv-1 infection by targeting mitochondrial dysfunction

HIGHLIGHTS

  • who: Aljawharah Alrubayyi from the Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, Division of Infection and Immunity have published the research work: Functional Restoration of Exhausted CD8 T Cells in Chronic HIV-1 Infection by Targeting Mitochondrial Dysfunction, in the Journal: (JOURNAL)
  • what: With increased appreciation of the importance of immunometabolism in shaping effective CD8 T_cell responses this study provides new insights into the metabolic features of exhausted CD8 T_cells in HIV-1 infection and identifies potential new targets for therapeutic restoration of antiviral responses. The authors have not evaluated the effects . . .

     

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