HIGHLIGHTS
- who: L-type Ca and colleagues from the Ludwig Maximilian University of Munich, Germany have published the research: Functional tuning of Vascular L-type Ca channels, in the Journal: (JOURNAL)
- future: And future directions This mini-review summarizes current thinking on how the functional tuning of L-type Ca2+ channels could be tuned in vascular smooth muscle to impact Ca2+ influx and tissue contractility.
SUMMARY
The RhoA/Rho-kinase pathway is particularly important, and when inhibited pharmacologically (e_g, Y27632 or H1152), MYPT1 phosphorylation, myosin light chain phosphatase activity and smooth muscle . . .
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