G protein-dependent activation of the pka-erk1/2 pathway by the striatal dopamine d1/d3 receptor heteromer involves beta-arrestin and the tyrosine phosphatase shp-2

HIGHLIGHTS

  • who: Federica Bono and colleagues from the Section of Pharmacology, Department of Molecular and Translational Medicine, University of Brescia, Viale Europa, Brescia, Italy have published the paper: G Protein-Dependent Activation of the PKA-Erk1/2 Pathway by the Striatal Dopamine D1/D3 Receptor Heteromer Involves Beta-Arrestin and the Tyrosine Phosphatase Shp-2, in the Journal: Biomolecules 2023, 13, x FOR PEER REVIEW of 12/09/2017
  • what: The authors define the intracellular signaling activated by the D1R/D3R heteromer that was analyzed in transfected Hek293 cells and primary cultures of mouse striatal neurons . . .

     

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