HIGHLIGHTS
- who: Jochen Spiegel from the Institute, Li Ka Shing Centre, UK University of have published the article: G-quadruplexes are transcription factor binding hubs in human chromatin, in the Journal: (JOURNAL)
- what: The authors demonstrate that in a chromatin context this binding interaction is competed out with a small molecule. The authors report that numerous TFs are recruited to sites of endogenous G4s in human chromatin. This analysis showed that many TFs were enriched at endogenous G4 sites and is immediately suggestive of direct TF-G4 interactions (Fig 1a and Additional file 1: Fig S2 . . .
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