Gabaergic synapses onto sst and pv interneurons in the ca1 hippocampal region show cell-specific and integrin-dependent plasticity

HIGHLIGHTS

  • who: Patrycja Brzdu0105k from the DepartmentMedical University have published the paper: GABAergic synapses onto SST and PV interneurons in the CA1 hippocampal region show cell-specific and integrin-dependent plasticity, in the Journal: Scientific Reports Scientific Reports of 15/01/2015
  • what: Altogether, the authors show that u03b15u03b21 integrins exert cell-specific modulation of GABAergic plasticity and, most interestingly, this effect on mIPSC amplitude is opposite in the case of FS PV + and SST + INs.
  • how: The potentiating effect observed for FS interneurons (Fig 1 c e-g) was specific to RGD because . . .

     

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