Galectin-3 is a non-classic rna binding protein that stabilizes the mucin muc4 mrna in the cytoplasm of cancer cells

HIGHLIGHTS

• who: Lucie Coppin from the (UNIVERSITY) have published the paper: Galectin-3 is a non-classic RNA binding protein that stabilizes the mucin MUC4 mRNA in the cytoplasm of cancer cells, in the Journal: (JOURNAL) of 06/03/2017
• what: The authors focused on the CARE motif, which is conserved in the 3′​UTR of mouse and rat Muc4 and absent from the 3′​UTR of MUC1 mRNA that is not stabilized by Gal-3. This analysis demonstrated that Gal-3 interacts with several mucin mRNAs such as MUC4 and MUC16 but not with those . . .
  

   

  

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