Gasdermin d independent canonical inflammasome responses cooperate with caspase-8 to establish host defense against gastrointestinal citrobacter rodentium infection

HIGHLIGHTS

• who: Elien Eeckhout from the The Gsdmd-/- [21], Casp1/11-/- [54], Casp1-/- [55], Casp11-/- [17], Mlkl-/- [56], and, /-Ripk3-/- [28, , ] genetic mouse models used in this study, either generated on C BL/ J background or backcrossed at least ten generations to C BL/ J background, were described previouslyMore complex genetic mouse models used in this study were generated by intercrossing the above lines. All mice used in in vivo infection experiments were age- and sex-matched littermates. All mice were housed in individually ventilated cages in the specific pathogen-free animal facility of the IRC-VIB. Food . . .
  

   

  

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