HIGHLIGHTS
- who: Kole H. Buckley and collaborators from the Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Civic Center Blvd, Philadelphia, PA, USA have published the research work: Gastric Cancer Risk and Pathogenesis in BRCA1 and BRCA2 Carriers, in the Journal: Cancers 2022, 5953 of 15/Nov/2022
- what: While the studies suggest improved responsiveness of BRCA1/2associated GCs to platinum-based intervention, other DNA damaging agents such as PARP inhibitors (PARPi) may also prove useful as PARPi have shown selective killing of BRCA1/2 mutant tumor cells .
- future: Given . . .
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