HIGHLIGHTS
- who: Andy K. M. Lam from the University of have published the research: Gating the pore of the calcium-activated chloride channel TMEM16A, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: The study has located strongly right-shifting mutants in the vicinity of the Ca2+ binding_site, certain moving parts of u03b16 and interacting regions between u03b1-helices 5, 6, 7, and 8 (Fig 1b-e). As the nature of rectification depends on the position of rate-limiting barriers11, this analysis provides further evidence for the location of the gate with respect to the anion conduction . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.