Gc-ms studies on the conversion and derivatization of -glutamyl peptides to pyroglutamate (5-oxo-proline) methyl ester pentafluoropropione amide derivatives

HIGHLIGHTS

  • who: Alexander Bollenbach and Dimitrios Tsikas from the Core Unit Proteomics, Institute of Toxicology, Hannover Medical School, Hannover, Germany have published the paper: GC-MS Studies on the Conversion and Derivatization of -Glutamyl Peptides to Pyroglutamate (5-Oxo-Proline) Methyl Ester Pentafluoropropione Amide Derivatives, in the Journal: Molecules 2022, 27, 6020. of 12/08/2022
  • what: Because of the highly characteristic structural feature of GSH, that is its u03b3-L-glutamyl moiety, the aim of this study was to develop a stable-isotope dilution GC-MS method for the specific measurement of u03b3-L-glutamyl . . .

     

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