Gcp16 stabilizes the dhhc9 subfamily of protein acyltransferases through a conserved c-terminal cysteine

HIGHLIGHTS

  • who: . et al. from the University of Glasgow, United Kingdom have published the research: GCP16 stabilizes the DHHC9 subfamily of protein acyltransferases through a conserved C-terminal cysteine, in the Journal: (JOURNAL)
  • what: The authors sought to better understand the role of GCP16 in the DHHC9-GCP16 PAT complex, and the authors investigated the stability of the DHHC9 disease mutants. The study demonstrates that a subgroup of the larger DHHC protein family that includes DHHC9, 14, 18, 5, and 8 all require accessory_proteins for their stability in_vitro. Taken together, the authors reason that the CCM . . .

     

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