HIGHLIGHTS
- who: Marie Plissonneau from the Laboratoire de Chimie et Biologie Métaux, Université , France have published the Article: Gd-nanoparticles functionalization with specific peptides for ß-amyloid plaques targeting, in the Journal: (JOURNAL)
- what: In this work, ultra-small gadolinium-nanoparticles were successfully grafted with two peptides targeting Aβ(1- 42) fibrils (KLVFF and LPFFD).
SUMMARY
Amyloidoses constitute a wide range of human diseases which are related to the conversion of soluble proteins into well-organized and insoluble fibrillar deposits, due to protein misfolding and self-association into amyloid aggregates enriched with . . .
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