Gene coexpression network characterizing microenvironmental heterogeneity and intercellular communication in pancreatic ductal adenocarcinoma: implications of prognostic significance and therapeutic target

HIGHLIGHTS

• who: Chengsi Wu from the University of Michigan, United States have published the paper: Gene Coexpression Network Characterizing Microenvironmental Heterogeneity and Intercellular Communication in Pancreatic Ductal Adenocarcinoma: Implications of Prognostic Significance and Therapeutic Target, in the Journal: (JOURNAL)
• what: Unlike other single-cell studies in pancreatic cancer that analyze general ligand-receptor- directed cell interactions , the authors focused on intercellular crosstalk directed by the hub genes within coexpression networks.
• how: The single-cell RNA-seq data were analyzed by the u2018Seurat` package . To test this finding in the external cohort the same consensus . . .
  

   

  

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