Gene suppression of transketolase-like protein 1 (tktl1) sensitizes glioma cells to hypoxia and ionizing radiation

HIGHLIGHTS

• who: Sonja Heller et al. from the DrSenckenberg Institute of Neurooncology and University Cancer Center (UCT), Partner Site Frankfurt/Mainz, Frankfurt am Main, Germany have published the paper: Gene Suppression of Transketolase-Like Protein 1 (TKTL1) Sensitizes Glioma Cells to Hypoxia and Ionizing Radiation, in the Journal: (JOURNAL) of 17/03/2009
• what: The authors provide evidence that TKTL1 renders cells more resistant to radiation therapy and to hypoxic conditions.
• how: The authors analyzed HCT-116 colon shown above we the authors repeated keykey experiments using another shRNA sequence and Toverify verifythe thedata . . .
  

   

  

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