Gene therapy using recombinant aav type 8 vector encoding tnap‐d10 improves the skeletal phenotypes in murine models of osteomalacia

HIGHLIGHTS

• who: Amadeu De Oliveira and colleagues from the University of Edinburgh has made every reasonable effort to ensure that Edinburgh Research Explorer Human Genetics Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA have published the article: Gene Therapy Using Recombinant AAV Type 8 Vector Encoding TNAPu2010D10 Improves the Skeletal Phenotypes in Murine Models of Osteomalacia, in the Journal: (JOURNAL)
• what: The authors aimed to determine efficacy of AAV8-TNAP-D10 in improving skeletal and dental phenotype in AlplPrx1/Prx1 and Phospho1/ mouse models of late-onset (adult) HPP and pseudo-HPP respectively . . .
  

   

  

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