HIGHLIGHTS
- who: Susanna Su00e4isu00e4-Borreill from the (UNIVERSITY) have published the research work: General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions, in the Journal: (JOURNAL) of 13/01/2023
SUMMARY
The authors reveal a novel function of Taf4 in antagonizing Polycomb Repressive Complex 2 (PRC2) to maintain the SC gene_expression program. The effect of Taf4 inactivation on gene_expression was investigated by RNA-seq in the intestine of E17.5 Taf4IEndoC fetus vs. control littermates (Supplementary Table 1), and in the ileum of adult Taf4IEC vs. control Taf4lox . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.