Generation and clinical potential of functional t lymphocytes from gene-edited pluripotent stem cells

HIGHLIGHTS

  • who: Rongqun Guo from the (UNIVERSITY) have published the Article: Generation and clinical potential of functional T lymphocytes from gene-edited pluripotent stem cells, in the Journal: (JOURNAL)
  • what: The study of HSPC transplantation [138-142], as well as disorders of hematopoiesis, lymphatics, and immunity [143] has facilitated the understanding of the HSC differentiation cascade.

SUMMARY

    Edited T_cells are being studied for engineering chimeric antigen receptor (CAR) T_cells which are a form of major cellular therapy for hematological malignancies. The application of cell immunotherapy is limited by the availability of autologous . . .

     

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